Suppression growth of Cancer cells / NK Cells Activation

Suppression growth of
cancer cells by proteoglycan


Attacking cancer cells by activating NK cells

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Cancer cells spread by performing angiogenesis (new blood vessel branches off from the existing one and structures a vasoganglion).
It is clarified that proteoglycan has a function to block this angiogenesis of cancer cells to suppress their growth.
Midkine which is a sort of growth factors is a substance to promote transfer and survive of cancer cells.
In various cancers as esophageal cancer, stomach cancer, large bowel cancer, liver cancer, pancreatic cancer, thyroid cancer, lung cancer, breast cancer, bladder cancer, uterine cancer, ovarian cancer or prostatic cancer, increased midkine expression is confirmed with about 80% of probability.
Glucosaminoglycan contained in proteoglycan suppresses transfer and survive of cancer cells by combining with this midkine.
Also, oral administration of proteoglycan blocks function of a substance which is called metal proteinase which is generated when cancer transfers.
By these two functions, proteoglycan prevents spread and expansion of cancer by blocking angiogenesis of cancer cells.

Moreover, a test result is announced that oral administration of natural proteoglycan activates NK cells which are natural immunity factor to work against tumor cells or viral infection cells.
NK cells are the main natural immunity capacity to attack a newly produced cancer cells to lead them to be eliminated. This function is also greatly expected from the viewpoint of preventive medicine.


■NK cell activation in human blood increase by proteoglycan intake

Test summary
Target:
Healthy 6 women from 40s to 60s.

Steps:
Drank the PG solution 100ml with high purity proteoglycan 100mg or equivalent two times a day before breakfast and before going to bed for continuous 12 weeks, and measured their blood 2 times before and after ingestion at the third party organization (Otemachi Park Clinic/Chiyoda-ku Tokyo)

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Before and after drinking, statistically superior increase in NK cell activation was seen.

■Transition before and after medication of proteoglycan
   (100mg x 2/day, 12 weeks)

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Are you interested in Proteoglycans?
If you want to get it, visit this page.